AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Functional Immunology and Innovative Technologies (FIIT) at the AbbVie Cambridge Research Center, MA is seeking a highly motivated and experienced scientist with cell and molecular biology laboratory experience to join the CRISPR Center of Excellence, working collaboratively with FIIT teams to advance the AbbVie immunology pipeline. This position requires passion, attention to detail, prior hands-on experience, and teamwork.

Responsibilities:

• Independently performs cellular and molecular biology laboratory procedures, including immune cell culture, cellular functional assays, lentivirus generation, transfection, electroporation, and single cell cloning, nucleic acid and protein extraction, isolation, and purification, DNA sequencing, PCR, qRT-PCR, Western blot
• Support small molecule and biologics drug development
• Support CRISPR screening for target identification
• Support target biology validation using genetic tools, including gene overexpression via ORF; CRISPR-based technologies; RNAi; mutagenesis; validation of genetic manipulations.
• Effectively interpret results to peers and senior research staff
• Work collaboratively on projects across multiple pipeline programs
• Maintain accurate laboratory records and data.
• Maintain expert proficiency in laboratory techniques and passionately learn additional workflows in support of new projects and adjacent teams

Basic:

• Bachelor’s or master’s degree in molecular biology, immunology or other biological sciences with 5+ years (MS) or 7+(Bs) hands-on experience
• Skillful in cellular and molecular biology techniques, such as mammalian cell culture, lentivirus production, PCR, and gel electrophoresis; experience in genomic DNA isolation and validation of genomic edits, nucleofection using the Lonza 96 shuttle system
• Experience with a wide range of cell-based assays
• Solid understanding of genetic tools such as CRISPR and RNAi-based technologies
• Experienced in gene editing, RNAi, CRISPRa/i, or CRISPR KO strategies
• Prior industry experience
• Good communication, both speech and writing, to a variety of audiences
• Ability to collaborate with peers and their teams

Preferred Experience:

• Experience with functional CRISPR screening
• Experience in small molecule drug development and screening
• Hands-on experience with immunoassays including cell culture, FACS, ELISA, WB is preferred
• Bioinformatics experience is a plus

Key AbbVie Competencies:

• Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance
• Learns fast, grasps the “essence” and can change course quickly where indicated
• Raises the bar and is never satisfied with the status quo
• Creates a learning environment, open to suggestions and experimentation for improvement
• Embraces the ideas of others and nurtures innovation to make possibilities real

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​​

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• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​​

  
  

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​​

  
  

• This job is eligible to participate in our short-term incentive programs. ​​

  
  

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Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html 

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html